Bio-ceramics with clinical applications by Maria Vallet-Regi

By Maria Vallet-Regi

This booklet deals a different process that hyperlinks the fabrics technological know-how of bioceramics to medical wishes and applications.

Providing a established account of this hugely energetic region of analysis, the e-book experiences the scientific purposes in bone tissue engineering, bone regeneration, joint alternative, drug-delivery structures and biomimetism, this ebook is a perfect source for fabrics scientists and engineers, in addition to for clinicians.

From the contents:

Part I Introduction

1. Bioceramics
2. Biomimetics

Part II Materials

3. Calcium Phosphate Bioceramics
4. Silica-based Ceramics: Glasses
5. Silica-based Ceramics: Mesoporous Silica
6. Alumina, Zirconia, and different Non-oxide Inert Bioceramics
7. Carbon-based fabrics in Biomedicine

Part III fabric Shaping

8. Cements
9. Bioceramic Coatings for clinical Implants
10. Scaffold Designing

Part IV learn on destiny Ceramics

11. Bone Biology and Regeneration
12. Ceramics for Drug Delivery
13. Ceramics for Gene Transfection
14. Ceramic Nanoparticles for melanoma Treatment

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2002) Synthesis of porous hydroxyapatites by combination of gelcasting and foams burn out methods. J. Mater. Sci. -Mater. , 13, 1193–1197. 39. , Huang, X. and Chen, Y. (2005) Preparation and characterization of interpenetrating phase TCP/HA/PLGA composites. Mater. , 59, 4000–4005. 40. , Vallet-Regi, M. A. (2002) A new method to produce macropores in calcium phosphate cements. Biomaterials, 23, 3673–80. 310 Bioceramics with Clinical Applications 41. C. et al. (2003) In vivo bone response to porous calcium phosphate cement.

87. E. and Ramakrishna, S. (2006) A review on electrospinning design and nanofibre assemblies. Nanotechnology, 17, R89–R106. 88. , Pingguan-Murphy, B. and Osman, N. (2012) Progress of key strategies in development of electrospun scaffolds: bone tissue. Sci. Technol. Adv. , 13, 043002(13 pp). 89. H. E. (2005) Nanofiber generation of gelatinhydroxyapatite biomimetics for guided tissue regeneration. Adv. Funct. , 15, 1988–1994. 90. J. et al. (2006) Electrospun silk-BMP-2 scaffolds for bone tissue engineering.

While the fiber jet is traveling toward the grounded collector it undergoes a chaotic whipping instability. The fiber jet is deposited on the collector which can be rotating and translating, as depicted here architectures by using nanofibers, which are characterized by entangled fibers and a densely packed membranous structure [87]. This limitation makes it suitable to use in combination with an RC-assisted process as mentioned above [83, 84]. As has been commented above, the great advantage of electrospinning technology is the accurate control of fiber size, porosity, and fiber shape by different processing variables, such as applied voltage, polymer melt flow rate, capillary–collector distance, polymer/ceramic concentration, solvent volatility, and solvent conductivity [22].

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