Biomaterials and stem cells in regenerative medicine by Murugan Ramalingam, Seeram Ramakrishna, Serena Best

By Murugan Ramalingam, Seeram Ramakrishna, Serena Best

''This ebook bridges the space in experimental ways and figuring out one of the key parts of biomedical examine. It presents all-important elements facing the elemental technology concerned about constitution and homes, recommendations and technological suggestions in processing and characterizations, and purposes of biomaterials and stem cells in tissue regeneration. The insurance levels from basic ideas to Read more...

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2010) Seal et al. (2001), Tabesh et al. (2009) Seal et al. (2001), Cho et al. (2006) Seal et al. (2001), Jiang et al. (2010), Puppi et al. (2010) Identification and Application of Polymers as Biomaterials 11 12 Biomaterials and Stem Cells in Regenerative Medicine of manufacture, the ability to design complex shapes, the ability to mass produce cost effectively, and their availability with a wide range of physical and mechanical properties. The polymers used for orthopedic application can either be from synthetic or natural origins.

J Biomed Mater Res 79A:1–5. , and Bradley M. 2008. Screening for polymorphs on polymer microarrays. J Comb Chem 10:24–27. Y. 2010. Temporal Augmentation Using a Polytetrafluoroethylene Implant With the Assistance of an Endoscope. Aesth Plast Surg 34(6):701–704. Liu X. X. 2004. Polymeric scaffolds for bone tissue engineering. Ann Biomed Eng 32:477–486. , and Guillemin G. 1999. Effects of chitosan on rat knee cartilages. Biomaterials 20(20):1937–1944. L. 2004. Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: State of the art and recent developments.

Many groups have investigated the activity and biological properties of cells entrapped in alginate in vitro (Bouhadir et al. 2001). Alginate has also been examined in vivo for use in craniofacial cartilage replacement and as cartilage plugs to prevent vesicoureteral reflux (Paige et al. 1996). Researchers have also modified alginate with adhesive peptides in order to encapsulate anchorage dependent and independent cells (Rowley et al. 1999; Shin et al. 2004). Alginate and agarose (or ionic and thermoresponsive polymers in general) provide little control over the gelation process; particularly in a clinical setting once cross-linking is induced, by the addition of an ionic solution or a temperature change, the process cannot be stopped or accelerated.

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