By Patrick Guilfoile
Chook pox was once a ceremony of passage for kids and used to be usually regarded upon as only a nuisance, even though this sickness may cause problems in a few humans. This name provides an summary of this illness attributable to a herpes virus referred to as the varicella-zoster virus, explaining the signs of the sickness.
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Additional info for Chicken Pox (Deadly Diseases and Epidemics)
41 42 Chicken Pox Cell-to-cell Spread of Infection Viruses that are located on the surface of infected cells are capable of fusion with uninfected cells, and this leads to the spread of infection. 10 Immune System Response to Chicken Pox There are two branches of the immune system that coordinate the response to a chicken pox infection. One branch is called the innate immune system; the other branch is called the adaptive immune system. The innate immune system has the capability to respond to any pathogen and is always available, so it serves as the first line of defense against infection.
These cells are then incubated with radioactive chromium, which is retained inside the cells unless they are killed. The virus-infected, chromium-laced cells from the patient are then added to white blood cells from the same patient. These white blood cells had been previously exposed to varicella-zoster virus proteins to activate any cells that respond specifically to the varicella-zoster virus. If some of these white blood cells have been produced in response to a previous chicken pox infection, they will attack and kill the virus-infected cells, and radioactivity will be released into the culture medium and be readily detected.
Varicella immunoglobulin consists of blood serum from human donors who had high levels of antibodies to the varicella-zoster virus. It is prepared by taking blood from these donors, removing the red blood cells, and keeping the liquid. The liquid is then treated with ethyl alcohol, which concentrates the antibodies. Solvents and detergents are then added to the preparation to inactivate any blood-borne viruses that could otherwise be transmitted to the patient. An early study of the effect of varicella immunoglobulin on preventing chicken pox was reported in 1962.